Savannah Cat
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There are a number of drugs available to control inflammation and suppress the immune system in cats, an example of this is prednisolone { prednisone }, this is a very commonly used drug. This drugs belong to a class of drugs known as glucocorticoids so called because they are related to cortisone and they contain glucose in their molecules. These drugs are also related to the steroid hormones normally produced by the adrenal gland.
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The effects of glucocorticoids can be observed in every organ system in the body and these drugs should not be used except when necessary. Basically prednisolone is an anti-inflammatory drug which reduce the swelling, pain and redness associated with inflammation. But an important effect of these drugs is that at high and very specific doses, the immune system is suppressed.
These are prescription drugs and can only be obtained from a vet or by prescription from a vet.
What would you use prednisolone for in the cat?
The uses of prednisolone are wide and varied here are a few examples. It is used to treat allergies, inflammations and autoimmune diseases when the underlying cause cannot be treated or prevented. Examples include treatment of bronchial and lung diseases, skin diseases, intestinal diseases, spinal cord and brain diseases and diseases of the blood. Prednisolone is often a supplemental treatment for various cancers.
It is required as a supplement in the adrenal gland disorder, Addison’s disease (hypoadrenocorticism).
It is used as a treatment in bacterial (endotoxic) shock, it is also used used to treat a variety of immune system and autoimmune disorders .
What are the Precautions and Side Effects for Prednisolone
While generally safe and effective when prescribed by a veterinarian, prednisolone can cause side effects in some animals.
- Prednisolone should not be used in animals with known hypersensitivity or allergy to the drug.
- Prednisolone should be avoided in fungal infections.
- Prednisolone should not be used in pregnant animals, since it can induce labor.
- Extreme care must be taken when stopping prednisolone therapy. If an animal has been on prednisolone for an extended period of time, slow weaning off the drug is critical to avoid serious complications.
- Prednisolone may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with prednisolone. Such drugs include non-steroidal anti-inflammatories.
- Adverse effects include increased thirst and appetite, panting, vomiting, restlessness and diarrhea.
- Some animals may develop stomach ulcers from prednisolone use.
- Long-term use of prednisolone may result in loss of hair coat, weakening of the muscles, liver impairment and behavioral changes.
Dose rates
Medication should never be administered without first consulting your veterinarian.
Doses of prednisolone vary widely depending on the reason for prescribing.
Anti-inflammatory doses range from 0.1 to 0.3 mg per pound (0.2 to 0.6 mg/kg) up to twice daily.
Immuno suppressive doses range from 1 to 3 mg per pound (2 to 6 mg/kg) up to three times daily.
Doses for various diseases range between 0.1 to 3 mg per pound (0.2 to 6 mg/kg).
The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects.
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Scott Nimmo BVMS MRCVS
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