Drug Fact Sheet : Acetazolamide also known as Diamox and Dazamide.
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Description :
Acetazolamide while it is a is a sulfonamide drug it’s main use is as a carbonic anhydrase inhibitor. This class of drug acts to reduce the flow of certain fluids in the body, notably in the eye but also elsewhere such as the kidneys. In veterinary medicine it is commonly used to treat glaucoma, sometimes as a diuretic in cases of congestive cardiac failure and occasionally in the treatment of epilepsy where it acts to stabilise neurone discharge.
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Points to watch :
1. It should not be used in dogs with marked kidney or liver disease.
2. Ideally the effects of this drug should be monitored by periodic checks of the dog’s intra-ocular pressure. { The pressure within the eye ball }
3. It is not suitable for all types of glaucoma so the veterinary surgeon in charge of the case has to be clear of the diagnosis.
4. Side effects are possible and these commonly could include lethargy, poor coordination, skin rashes, sensitivity to light, abnormal blood pictures, vomiting and diarrhoea.
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Dose rates :
The dose rates for this drug are variable depending on the severity of the condition being treated. In dogs, the usual dose is 3.5 to 5 mg per pound (7 to 10 mg/kg) every 6 hours when treating glaucoma. sometimes Acetazolamide is given as a single dose of 25 mg per pound as a one off dose for glaucoma.
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Please note this is a concise fact sheet which is given for your interest and education only and should not be regarded as an inducement to self treat your dog. Treatment with prescription drugs is best done by your vet. Much more extensive and detailed information will be found in the appropriate professional data sheet for each drug.
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