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An article from a qualified veterinary surgeon. Acepromazine, ACP, Acetyl Promazine For The Dog, Dose Rates, Side Effects.
Description :
Acetyl promazine { Acepromazine, ACP } is a drug which is commonly used as a tranquiliser in the dog. Its exact mechanism of action unknown but some authorities think it acts to block the dopamine receptors in the brain. It is available in both tablet and injectable forms. It is used as a pre-medication as part of common anaesthetic protocols, sedation for minor procedures, to reduce fear and anxiety say when there will be fireworks and is a good travel sickness drug.
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Points to watch/ Side Effects :
1. ACP may interact with certain drugs, these may include narcotics, barbiturates, propranolol, epinephrine, antacids and antidiarrheal medications.
2. Many vets avoid using this drug in Boxers as it may cause changes in their heart rythm. It would in fact be best avoided in any breed of dog with an existing heart condition.
3. It should be avoided in dogs which have a history of seizures or epilepsy as it can excerbate or bring on fits in these animals.
4. It has been noted that large breeds of dog are particularly sensitive to acepromazine and the minimum dose possible should be used in these breeds.
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Dose rates :
The usual dose rate of ACP in tablet form is between 0.5 to 1.5 mg per pound (1 to 3 mg/kg) of your dog’s bodyweight. Given as an injectable the usual injectable dose is 0.01 to 0.1 mg per pound (0.02 to 0.2 mg/kg). Normally the injectable dose should not exceed 3 mg total, you can see from the above that the injectable dose is considerably smaller than the oral dose.
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Please note this is a concise fact sheet which is given for your interest and education only and should not be regarded as an inducement to self treat your dog. Treatment with prescription drugs is best done by your vet. Much more extensive and detailed information will be found in the appropriate professional data sheet for this drug, which you can read HERE.
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